শুক্রবার, ৩০ নভেম্বর, ২০১২

Blanca Eggenschwiler: Dating Joe Jonas?

Source: http://www.thehollywoodgossip.com/2012/11/blanca-eggenschwiler-dating-joe-jonas/

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Groupon CEO Andrew Mason Has ?Tough Fight ... - Yahoo! Finance

Three news stories on Wednesday appeared that reported essentially the same thing:

Board members at Groupn (GRPN) were discussing firing the company's CEO Andrew Mason.

These news stories did not cite each other. Rather, they cited "sources" close to the situation. (Kara Swisher at All Things D broke the story.* Then Bloomberg and the Wall Street Journal followed).

Often, when separate news stories contain essentially the same information and don't cite each other, it means that a person or company wants the information out there.

In the case of the Groupon, it was not immediately obvious who stood to gain from the Andrew Mason information.

It didn't help Andrew Mason, certainly.

And it didn't help the company, whose leadership was suddenly thrown into limbo.

And it didn't help the board as a whole, which looked like it was stabbing its CEO in the back.

It seemed unlikely that high-quality publications like All Things D, Bloomberg, and the Wall Street Journal would run with secondhand information. So it seemed the information had come directly from (or at the behest of) one or more of the board members who are discussing firing Mason.

Judging from the Wall Street Journal's story, which cited "fractures" and "clashes" between Andrew Mason and board members Eric Lefkofsky and Brad Keywell, it's not hard to guess who those board members might be.

In any event, leaking information like that was a cutthroat thing to do.

And it put Andrew Mason in an incredibly awkward position.

For one thing, it forced him to address in public the question of whether the board might fire him, which he did at the Business Insider Ignition conference. Mason had a good answer for that question: With the stock getting clobbered, of course the board was discussing whether he is the right guy for the job. But boards generally have those discussions in private, not in newspapers.

Importantly, if everyone on the board wanted to fire Mason, there would have been no need to leak the story. The board could just have canned Mason at the upcoming meeting and announced the news when it was a fait accompli. So it seems likely that a board member or two want to oust Mason and other board members don't--and that the ones who do want to oust him blindsided him.

(That was the impression I got in our interview, by the way--that Mason had been blindsided. He was articulate and composed, but he also seemed almost resigned to the fact that he was going to get canned).

It will be interesting to one day get the full story.

It will also be interesting to see how the situation plays out.

And inasmuch as someone on the Groupon board apparently wants us to have a public discussion about whether Andrew Mason should be canned, let's go ahead and have one.

The fire-Mason case is clear:

  • Groupon's stock has had an abysmal year since its IPO a year ago.
  • Groupon's international business is imploding.
  • The growth of Groupon's core daily deal business has slowed to a crawl, and the product still clearly needs tuning (there are too many anecdotal stories of merchants not liking the product)
  • There has been some senior management turnover
  • A big part of the problem at the company is external perception (which starts at the top)
  • Andrew Mason has only a few years of business experience and is now responsible for turning around and managing a massive global corporation, winning over Wall Street and the media, instilling passion and confidence in tens of thousands of rattled customers and employees

The give-Mason-more-time case, however, is also compelling:

  • Groupon has likely grown faster than any company in history--from zero to $2.5 billion in revenue, 12,000 employees, and profitability in less than four years
  • Groupon is still growing
  • Groupon is making money
  • Groupon has crushed almost all of its competitors
  • Groupon has successfully launched a new business--merchandise--that is already doing more than $1.5 billion of annualized revenue
  • Groupon's North American business is still doing well--it's the acquired companies in Europe that are the problem
  • Mason has a lot left to learn, but he is learning quickly
  • All companies go through rough periods.

What decision will the board make? What's the right decision?

That's a tough one.

In my opinion, it depends a lot on Andrew Mason.

Andrew Mason has led Groupon this far (and very few observers appreciate how spectacularly hard that has been to do). If Andrew Mason wants to fight to keep his job, commits to learning more about how to run a multi-national corporation and communicate better with Wall Street and the media, and remains excited and passionate about his job, then he should be given more time. Not an indefinite amount of time, but more time.

If, on the other hand, Andrew Mason has learned that managing a huge global corporation, dealing with the media and investors, and continuing to build and manage a top-notch senior executive team is just not as much fun or as rewarding as leading Groupon in the early years, then he should step aside (or get canned).

This, by the way, is not a new situation for a founder-CEO to find himself in.

The skills and leadership ability required to grow a startup are different than those required to turn around and manage a vast global corporation. And many talented entrepreneurs and executives decide that they prefer one to the other.

I have huge respect for Andrew Mason for doing the interview today. Most CEOs would have cancelled the conference appearance. I also have huge respect for what Mason and his team have accomplished at Groupon over the past three years.

If Mason wants some more time to prove himself and fix Groupon, the board should give him more time.

If he doesn't, I hope he resigns quickly, helps hire a great new CEO, and then eventually gets more credit for building the company than he has to date.

The reason that leak was so ruthless, though, is that it will be hard to recover from.

Groupon's CEO has been placed in limbo.

To resolve the situation in Mason's favor would require the resignation of the board members who want him gone. But even this wouldn't fix it. Everyone would know why these board members were quitting--because they had lost confidence in the CEO--and that wouldn't help Mason's authority, either.

Even if Andrew Mason wants to fight for his job, in other words, it will be a tough fight to win.

Whoever stabbed him in the back knew what they were doing.

Follow The Daily Ticker on Facebook!

More Groupon coverage from The Daily Ticker:

Groupon Stock Plummets After Poor Q3 Earnings: Has It Hit a Wall?

Groupon's Move into Mobile Payments: Hail Mary or Savvy Strategy?

Groupon Blows It Again, Restates Earnings as Customers Demand Refunds

Web 2.o Bust? Groupon's Early Investors Flee

Source: http://finance.yahoo.com/blogs/daily-ticker/groupon-ceo-andrew-mason-tough-fight-keep-job-160315102.html

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বৃহস্পতিবার, ২৯ নভেম্বর, ২০১২

New Principal & Chief Executive announced for new College

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Source: http --- Wednesday, November 28, 2012
Following the announcement in February 2012 that Deeside College and Yale College would merge, in August 2013, the new Chair of the Shadow Board of Governors Mr John Clutton has announced the appointment of the Principal & Chief Executive Designate of the new College. Mr Clutton said ?Following a rigorous selection process, I am delighted to announce that current Deeside College Principal Mr David Jones has been appointed as the Principal & Chief Executive Designate for the merged College. The full shadow board of governors ratified the appointment at the meeting on the 14th November and we are delighted that we will be entering the merger with one of the most respected Principals in Wales at the helm. In Mr Jones we have found a dynamic leader with a clear history of success in further education management who will lead the new College with the same drive and determination for excellence that we have seen during his time at Deeside College.? The announcement was backed by Vice Chair Mr Ray Wells who added, ?We are laying the foundations for a College that will serve North East Wales for many years to come. It will educate & support skills development and employability for over 7000 full time students each year and employ over 1500 people. In David Jones we have found someone with the skills, experience and ambition to deliver the commitments set out in the rationale for merger.? Speaking after his appointment Mr Jones said ?It wi ...

Source: http://www.yale-wrexham.ac.uk//news/new-principal-chief-executive-announced-for-new-college-1/

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Neil Young 'Waging Heavy Peace' in Live Twitter Q&A to Promote Memoir

Books & Review | Cole Garner Hill

Updated: Nov 27, 2012 05:10 PM EST

waging heavy peace

(Photo : Barnes and Noble) A first time author, Young wrote his memoir naturally, as things came back to him, and says he takes life the same way.

Old dogs can learn new tricks. While he might be a rocker in his twilight years, musician Neal Young continues to prove he can surprise fans just as he did when he first hit the stage 50 years ago. Young will participate in a live Twitter event to promote his new memoir "Waging Heavy Peace" on Nov. 28.

According to a press release from Young's publisher, Penguin, the legendary singer-songwriter will hold a Q&A session about his autobiography as part of Book Club Twitter Chat, sponsored by Blue Rider Press and Penguin Online. The event will held on Nov. 28 from 7:30 pm - 8:30 pm (EST).

Like Us on Facebook

To participate and for updates, follow @BlueRiderPress, @PenguinUSA, @NeilYoung or #WagingHeavyPeace.

[Ed: Event has been postponed, check back for updates]

Young first showed off his social media savvy in October when the artist took questions from fans to promote the release of his new album "Psychedelic Pill." The event was a hit for Twitter, and attracted lots of press attention.

"Waging Heavy Peace" was Young's first attempt at writing, but just like his music - that humble, shaggy-dog swagger, the virtue of cleverness in simplicity - he makes it look easy. It's endearing just how surprisingly unassuming, and willing he is in telling his story.

"Waging Heavy Peace" falls on the heavier side of rock n roll memoirs at 500 pages. Young meanders from talking about music, to his admittedly crazy ideas for eco-powered classic cars, to his family and medical conditions, including polio, epilepsy, and a brain aneurysm. Young likes to refer to himself as a crazy idealist, and even sometimes, still, a hippie. The book is filled with the rocker's plans for everything from his personal archives, to his charity foundations to feature films.

Young wrote his memoir as things naturally came back to him, just as he likes to live his life. Young's a gleeful walking contradiction, and he seems at peace with that. Having never written a book, or ever been "much of a reader," Young reportedly rejected more than half the edits to his manuscript.

"Writing is very convenient, has a low expense, and is a great way to pass the time," he writes. "I highly recommend it to any old rocker who is out of cash and doesn't know what to do next."

Just like much of his enigmatic music, Young leaves much to be interpreted in "Waging Heavy Peace," presenting his story through a series of episodes from his remarkable career. But there are still plenty of gems of wisdom and revealing anecdotes hiding in the clouded rough of his brain.

Young relates his struggles with anxiety in his youth, and addiction to smoking marijuana. The songwriter apparently had trouble completing even the simplest of tasks in public, like going to the store. Young "couldn't even handle the detail in the hallways, in the aisle ways - all the packages and everything used to just freak me out," he writes. Eventually, about halfway through the shopping trip, he would drop everything and need to leave the store.

Now, for the first time since 17, he's sober. "You know, I might have been an addict," he says, "but I didn't have the gene problem, where you really turn out to be an alcoholic. I just decided if I was going to stop smoking weed, I'd stop drinking, too."

The book's philosophical title comes from a conversation about Pono, his almost foolishly ambitious project to restore full audio quality to digital music. Without full audio quality, he says, music won't take you into "the spirit world." That seems to illuminate much of what continues to be so charming about Young, balancing idealism with profound, universal truths. Even if they are hippie-truths.

Young, who recently turned 68-years-old, is currently wrapping up his North American "Alchemy Tour" with Crazy Horse.

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Source: http://www.booksnreview.com/articles/1767/20121127/neil-young-waging-heavy-peace-live-twitter-q-a-promote-memoir.htm

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বুধবার, ২৮ নভেম্বর, ২০১২

We're Pleased to Partner with Society for New Communications ...

We?re thrilled today to announce that The Society for New Communications Research, a global nonprofit think tank and research and education foundation, and Social Media Today have formed a partnership to provide research, case studies, whitepapers and best practices to communications professionals and business leaders. The collaboration between our two organizations will bring the best independent, unbiased research and papers by SNCR's fellows to the Social Media Today audience.

For our members, the partnership will be bringing us a rich new source of terrific insight and research.?? SNCR?s thinking about social media over the years has blazed a lot of trails; not content to look at social media as purely as a new marketing tool, SNCR?s researchers have delved into the deeper issues around social media and politics, new roles for companies as creators of content, social media adoption in developing countries, and many more next-generation topics.? Their annual meetings are mind-bending opportunities to find out what will be happening not today, but tomorrow.

For our sponsors, this partnership will mean a new source of editorially independent content that can be branded and linked to inbound marketing efforts. We'll be producing white papers, exclusive posts, ebooks, and much more that will lend burnish to your brand, and attract new customers to your products.? SNCR?s methodologies are first-rate and their analysis acute.?? Their researchers? areas of expertise is broad, encompassing online community, social business adoption, social media globally, social media and impact, ?content marketing,? and more.? We?ll be able to bring new topics to SNCR, as well as let you know about current projects that may become part of your marketing plans.? Further, we?ll be able to use our syndication capabilities to make sure that your branded study receives the widest possible audience.

This partnership is a true benefit to both of our organizations, and please join me in thanking Jennifer McClure, Founder and CEO, and Gina Hernandez of SNCR in making this

About Society for New Communications Research (SNCR)

The Society for New Communications Research is a global nonprofit 501(c)(3) research and education foundation and think tank focused on the advanced study of the latest developments in new media and communications, and their effect on traditional media and business models, communications, culture and society. For more information, visit http://sncr.org.

About Social Media Today

Social Media Today is an independent, online community for professionals in PR, marketing, advertising or any other discipline where a thorough understanding of social media is mission-critical. Every day, we provide insight and host lively debate about the tools, platforms, companies and personalities that are revolutionizing the way we consume information.?

Source: http://socialmediatoday.com/robin-carey/1035596/were-pleased-partner-society-new-communications-research

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Boy Meets Boy, Jermyn Street Theatre, London

Published Wednesday 28 November 2012 at 12:53 by Paul Vale

Written in 1975, Boy Meets Boy is a sparkling musical comedy set against the backdrop of the abdication crisis in pre-war Britain. The big difference is that this is an alternative 1936, where gay relationships are perfectly acceptable and high society is quivering with excitement at the impending nuptials of Boston millionaire Clarence Cutler and British aristocrat Guy Rose. It?s a bizarre leap to take but writers Bill Solly and Donald Ward take it with impeccable flair, crafting an exquisite pastiche that manages at turns to be both cheerfully sentimental yet vaguely subversive. Solly?s music and witty lyrics pay affectionate homage to the likes of Porter and Berlin while the book, co-written with Ward manages in one fell swoop to put the word ?gay? back into the term ?gay musical comedy?.

Stephen Ashfield brings a sense of worldly realism to the commitment-phobic journalist, Casey O?Brien, breaking as many hearts as he does news stories. O?Brien career as a lothario is finally stalled by Craig Fletcher?s shy, sensitive Guy Rose, a beauty hidden behind geeky spectacles and bad hair. Ashfield and Fletcher make an adorable couple, pulling off the humour of the hilarious It?s A Boy?s Life at the same time as developing a romantic storyline that is as sentimental as it is satisfying. Beyond the romance there is the louche comic delivery of Ben Kavanagh, as jilted groom Clarence Cutler, providing many of the laugh-out-loud moments throughout the evening and a thoroughly committed ensemble, bringing colour and vivacity to Solly and Ward?s screwball comedy.

Director Gene David Kirk?s lucid direction, his swansong as artistic director for this venue, is complemented by Lee Proud?s bold choreography that mirrors both the romance and the wit of the piece. Boy Meets Boy might not be to everybody?s taste, but there is an unfailing sense of optimism about this show that makes it one of the most pertinent revivals of the year.

Production information

Jermyn Street Theatre, London, November 21-December 20

Author:
Bill Solly (book, music and lyrics), Donald Ward (book)
Director:
Gene David Kirk
Producer:
Jermyn Street Theatre
Cast includes:
Stephen Ashfield, Craig Fletcher, Johnjo Flynn, Ben Kavanagh, Anna Nicholas, Carly Mackelvie
Running time:
2hrs 15mins

Production information can change over the run of the show.

Source: http://feedproxy.google.com/~r/TheStageReviews/~3/p85Z3VAPNwg/boy-meets-boy

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GOP senators more troubled after Rice meeting

Sen. John McCain, R-Ariz., ranking Republican on the Senate Armed Services Committee, center, flanked by fellow committee members, Sen. Kelly Ayotte, R-N.H., left, and Sen. Lindsey Graham, R-S.C., right, speaks on Capitol Hill in Washington, Tuesday, Nov. 27, 2012, following a meeting with UN Ambassador Susan Rice. Rice met with lawmakers to discuss statements she made about the attack on the U.S. Consulate in Libya that left the ambassador and three other Americans dead. (AP Photo/Susan Walsh)

Sen. John McCain, R-Ariz., ranking Republican on the Senate Armed Services Committee, center, flanked by fellow committee members, Sen. Kelly Ayotte, R-N.H., left, and Sen. Lindsey Graham, R-S.C., right, speaks on Capitol Hill in Washington, Tuesday, Nov. 27, 2012, following a meeting with UN Ambassador Susan Rice. Rice met with lawmakers to discuss statements she made about the attack on the U.S. Consulate in Libya that left the ambassador and three other Americans dead. (AP Photo/Susan Walsh)

FILE - This April 14, 2012 file photo shows U.S. Ambassador to the United Nations Susan Rice speaking at U.N. headquarters. With congressional opposition softening, U.N. Ambassador Susan Rice could find her name in contention as early as this week to succeed Hillary Rodham Clinton as secretary of state. Her nomination to the top Cabinet job could signal the potential for a more robust intervention in world crises in President Barack Obama?s second term. (AP Photo/Craig Ruttle, File)

Sen. Lindsey Graham, R-S.C., a member of the Senate Armed Services Committee and the Senate Homeland Security Committee, center, accompanied by fellow Senate Armed Services Committee member, Sen. Kelly Ayotte, R-N.H.,, right, gestures while speaking to reporters on Capitol Hill in Washington, Tuesday, Nov. 27, 2012, after a closed-door meeting with UN Ambassador Susan Rice. (AP Photo/J. Scott Applewhite)

Senate Armed Services Committee member, Sen. Kelly Ayotte, R-N.H.,, center, accompanied by fellow Senate Armed Services Committee member, Sen. Lindsey Graham, R-S.C., right, speaks to reporters on Capitol Hill in Washington, Tuesday, Nov. 27, 2012, following a closed-door meeting with UN Ambassador Susan Rice. (AP Photo/J. Scott Applewhite)

(AP) ? Emerging from a closed-door meeting, three Republican senators said Tuesday they are more troubled than ever with comments made days after the deadly Sept. 11 raid in Libya by Susan Rice, the U.N. ambassador and President Barack Obama's possible choice for secretary of state.

Sens. John McCain, Lindsey Graham and Kelly Ayotte met privately with Rice and acting CIA Director Michael Morell for more than an hour on her much-maligned explanations of the attack on the U.S. diplomatic mission in Benghazi, Libya, that killed the U.S. ambassador and three other Americans.

Ayotte said Rice told the lawmakers that her comments in a series of national television interviews five days after the attack were wrong. However, that failed to mollify the three lawmakers, who have talked about blocking her nomination if the president taps her to succeed Secretary of State Hillary Rodham Clinton.

"We are significantly troubled by many of the answers that we got and some that we didn't get concerning evidence that was leading up to the attack on the consulate and the tragic death of four brave Americans and whether Ambassador Rice was prepared, or informed sufficiently, to give the American people the correct depiction of the events that took place," McCain told reporters.

Said Graham: "Bottom line I'm more disturbed now than I was before that 16 September explanation."

The three insisted that they need more information about the Libyan raid before they even consider Rice as a possible replacement for Clinton.

"I'm more troubled today," said Ayotte, who argued that it was clear in the days after the attack that it was terrorism and not a spontaneous demonstration prompted by an anti-Muslim video.

Despite lingering questions over her public comments after the Benghazi attack, Rice has emerged as the front-runner on a short list of candidates to succeed Clinton, with Sen. John Kerry, D-Mass., seen as her closest alternative.

The strong statements from the three senators clouded Rice's prospects only two days after Republican opposition seem to be softening. Rice planned meetings on Wednesday with Sen. Bob Corker of Tennessee, who is in line to become the top Republican on the Foreign Relations Committee, and Sen. Susan Collins, R-Maine.

Corker said Tuesday that he had concerns with a possible nomination.

"When I hear Susan talk she seems to me like she'd be a great chairman of the Democratic National Committee," Corker said. "There is nobody who is more staff supportive of what the administration does. That concerns me in a secretary of state."

Rice's series of meetings on Capitol Hill will be a critical test both for Republicans, who will decide whether they can support her, and the administration, which must gauge whether Rice has enough support to merit a nomination.

A senior Senate aide said the administration was sounding out moderate members of the Senate Foreign Relations Committee, such as Corker and Sen. Johnny Isakson, R-Ga. Assessing the prospects for Rice before Obama makes any announcement would avoid the embarrassment of a protracted fight with the Senate early in the president's second term and the possible failure of the nominee.

Rice is scheduled to meet with Sen. John McCain, R-Ariz., her most vocal critic on Capitol Hill, and Sen. Kelly Ayotte, R-N.H. McCain and Ayotte are members of the Senate Armed Services Committee.

On talk shows the weekend following the attack, which took place on the 11th anniversary of 9/11, Rice was given talking points that described the attack as a spontaneous protest of the film, even though the Obama administration had known for days that it was a militant assault.

Republicans called her nomination doomed, leading to a vigorous defense of her by Obama in his first postelection news conference. Since then, GOP lawmakers have appeared to soften their views. McCain, who said earlier this month that would he do everything in his power to scuttle a Rice nomination, said Sunday that he was willing to hear Rice out before making a decision.

Sen. Jim Inhofe, R-Okla., a member of the Senate Foreign Relations Committee, had issued a statement highly critical of Rice on the day of Obama's news conference. He indicated Monday that perhaps she didn't know what had transpired in Benghazi on the day of the attack.

"I assumed she had full knowledge of everything that went on. I'm not at all convinced of that now. She very well could have been thrown under the bus," Inhofe said in an interview. He said she hadn't requested a meeting but he would be glad to meet with her.

White House spokesman Jay Carney said Monday that the administration appreciated McCain's latest comments about Rice, but wouldn't say whether the president saw them as an opening to make the nomination. "Ambassador Rice has done an excellent job at the United Nations and is highly qualified for any number of positions," Carney said.

Several diplomats currently serving with Rice said that what she lacked in Clinton's star power, she could make up with a blunter approach that demands attention and has marked her tenure thus far at the United Nations.

Rice, who at 48 is relatively young, has been known to covet the job for years, but was passed over for Clinton in 2009. Since arriving in New York, she can point to a series of diplomatic achievements ? most notably the NATO-led air campaign that toppled Libyan leader Moammar Gadhafi and tougher sanctions against Iran and North Korea over their nuclear programs.

But Rice has also been criticized ? along with other Security Council leaders ? for the failure of the U.N.'s most powerful body to take action to end the 19-month civil war in Syria.

___

Associated Press writers Matthew Lee in Washington and Edith M. Lederer in New York contributed to this report.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/89ae8247abe8493fae24405546e9a1aa/Article_2012-11-27-Cabinet-Rice/id-1f34c6042cfe43b8bdf986a93debb2de

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Anti Wrinkle Cream that Contains Scientists' Proven Ingredients

Only the anti wrinkle cream that contains appropriate anti aging ingredients will work. No matter how costly a cream you buy and how sophisticated the beauty store and the jar is, it is the ingredients that work, not attractive packaging. In fact, creams that come with aggressive marketing and glossy ads are mostly hollow in their promises.

What a cream needs to work?

Three ingredients that scientists have proven to work on aging signs are Matrixyl 3000, Argireline, and Hyaluronic Acid. The cosmetic world regards them as the ultimate solution to wrinkle removal. They are not simple oils or moisturizers. These ingredients possess a unique set of abilities that show their prowess within the layers of the skin.

Matrixyl 3000 is an amazing skin fixer. It repairs damaged layers of the skin by penetrating deeply. It boosts collagen production and restructures the fibril network that degenerates due to lack of collagen. Studies show that this ingredient can reduce wrinkle visibility by 44 percent. Without the presence of this ingredient in an anti wrinkle cream, the cream is useless, as this is the one that restores one of the essential proteins, collagen, in the skin.

Argireline is a soothing agent. It is a peptide that relaxes facial muscles, which contract due to habitual facial expressions and contribute to forming creases on the face. This peptide works so well that dermatologists consider it to be the best alternative of botox. The latter paralyzes facial muscles, which is against nature. On the contrary, Argireline relaxes muscles, which is perfectly in compliance with nature.

Hyaluronic Acid (HA) is a natural and powerful hydrator found in the body. It removes toxins from body cells and tissues, and supplies oxygen and nutrients to them. It keeps joints and cartilage lubricated. Studies show that this compound has the ability to hold thousands of times its own weight in water. It means, without this Acid, skin cells dehydrate. This is what happens when you age ? HA declines and skin cells lose their water content, leading to loose and creased skin surface.

Imagine a wrinkle remover containing all the above ingredients. How powerfully it will work on an aging skin! The good news is that such an anti aging formula does exist in the market. Since the day of its launch, it has given other OTC creams a run for their money. It has stunned women and they are still not able to believe that such a formula exists.

The cream is non-sticky and seeps into skin pores, working with the damaged fibril structure and increasing levels of collagen and elastin. Regular usage of this cream creates a drastic difference on the face. Gradually, you will find your wrinkles and fine lines getting lighter, and dark spots and discolorations becoming blurred.

What?s the name of such cream?

The cream is Hydroxatone. This is not a single cream, but a skin care brand that has created a line of products for keeping skin young and beautiful. The brand has received an unbelievable response for it has given women the ultimate anti wrinkle cream.

Author's Bio:?

Hydroxatone offers Hydroxatone anti wrinkle cream as a risk free trial offer. You need not pay for the cost of this wrinkle remover. Visit the site and order.

Source: http://www.selfgrowth.com/articles/anti-wrinkle-cream-that-contains-scientists-proven-ingredients

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CallPlus slams Kiwihost customer service survey | Stuff.co.nz

CallPlus chief executive Mark Callander has hit back at a Kiwihost survey that slated the customer service record of its Slingshot subsidiary, saying statements made by Kiwihost were very misleading and accusing it of "poor research standards".

Kiwihost, a private firm that provides customer service training to businesses, released a survey earlier this month that accused the country's telcos of providing "shocking customer service" . It rated Slingshot lowest, with a "strongly negative rating" of -23. The lowest possible rating, if all respondents were dissatisfied, would be -100.

Callander said Kiwihost's survey was only completed by 600 respondents. Slingshot had about 10 per cent of the broadband market, so it was likely only about 60 of its customers were surveyed.

Kiwihost asked people to rate providers but didn't ask if those responding were a customer or had any personal experience of each company, he said.

"More concerning is there is no context to the question at all, so responses are entirely open to interpretation."

Callander said Kiwihost's claims were dramatically different to its own research, which involved randomly contacting 5000 of its customers each month. That showed Slingshot's customer satisfaction had been trending upwards, he said. "We have 150 proud contact centre staff based in New Zealand doing an amazing job and providing great service.

"Reports and statements from companies such as Kiwihost which provide minimal information and context are very damaging not only to Slingshot, but the industry in general," he said.

CallPlus has been trying to turn around its image over the past few years. Callander acknowledged to Fairfax Media this month that it had been tarnished by complaints and an aggressive "cold calling" telemarketing campaign using a call centre in India.

- ? Fairfax NZ News

Comments

Source: http://www.stuff.co.nz/business/7989355/CallPlus-slams-customer-service-survey

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peterm's Site - Attracting Customers Through Online Advertising

Internet has become the fastest means of communication among individuals across the world. It has also become the most effective means of connecting brand/business owners with their prospective customers. Online advertising also known as internet advertising or web advertising is one of the fast growing means of brand or business communication. This blog highlights a few secrets of attracting customers through online advertising.

Publishing unique articles or blogs about your business

It may surprise many brand or business owners, but it is true that publishing unique articles or blogs about your business helps in attractive various customers to your website thereby acquainting them about what your business offers. Ezine is one of the online publishing sites where you can publish your articles or blogs. A major advantage of publishing online articles or blogs is that it is usually free of cost and you can elaborately talk about your brand or business in detail. Customers who are directed to the publishing sites read the informative content. If the content sounds pretty interesting, they would be encouraged to adopt or buy the business or brand. Search Engine Marketing is one of the main tools of internet advertising. Writing articles and blogs and publishing them on various sites is also one of the main strategies of search engine marketing. Search engine optimizers make the most of this very strategy to promote their business among customers.

Making the most of Email marketing

Another secret of web advertising is to interact with customers through emails. Most of us do not forget to check our mail boxes. By presenting the brand message right through the inboxes of customers, advertisers can easily persuade them to go through the same. Email marketing is also a cost effective means of web advertising. Advertisers can sort out the mailing list of a particular email campaign and can target only those customers who will probably reach to the advertisement. A thorough demographic survey is however one of the assets of promoting a brand or business through email marketing.

Online advertising in any of its forms provides rich content and attractive graphic. Any visitor gets glued to the brand message because of such features. Most of the online ad campaigns convey interesting brand messages to customers which is why recall value is also pretty good through an online ad display. Banner advertising, virals, email and sms campaigns, PPC, pop ups etc. are some forms of online advertising adopted by brand owners to promote their products on web world.

Internet is a global platform for many products and services. Internet advertising is therefore the smartest means of brand communication. A brand or business advertised through online media can be accessed by customers from anywhere across the globe and also without any restraint of time factor. The message or information is available for 24 hours, 7 days a week, months and even for years. A website for a brand or business for example is one of the reliable means for anyone to access valuable information on the product or service. One can visit the website as many times as one prefers and also go through the information again and again. Repetitive readership is yet another advantage of creating an online presence of a brand or business.

source

Source: http://tapantaeverything.blogspot.com/2012/11/attracting-customers-through-online.html

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Source: http://petermuellir3.multiply.com/journal/item/1738/Attracting-Customers-Through-Online-Advertising-...

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Source: http://roosealice.posterous.com/peterm39s-site-attracting-customers-through-o

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Congressman Al Green Sends Letter to the Department of Housing ...

November 22, 2012 - (RealEstateRama) -- On November 21, 2012, Congressman Al Green sent a letter to the Department of Housing and Urban Development (HUD) as well as to the Department of Justice (DOJ) calling to their attention an invidious message, which referenced young African Americans, posted on the property of an apartment complex, located in the Ninth Congressional District. Congressman Al Green asked the agencies to take whatever action they deemed appropriate.

Full article: Congressman Al Green Sends Letter to the Department of Housing and Urban Development as well as the Department of Justice Concerning an Invidious Notice Posted on the Property of an Apartment Complex ...

No related posts.

154

Articles Category:

  • The New York City Housing Authority Continues Restoration and Remediation Efforts in Housing Developments Impacted by Hurricane Sandy
    New York, NY - November 21, 2012 - (RealEstateRama) -- Now that electricity, elevators, heat and hot water have been restored in all developments impacted by Hurricane Sandy, the New York City Housing Authority has moved to the next phase of its recovery plan: remediation and repair for individual housing units. NYCHA will clean and remove mold or mildew created by Hurricane Sandy inside individual apartments, in addition to efforts to remove all trash and debris from hallways, stairs and common areas. The work will first be concentrated in NYCHA developments in Far Rockaway and Coney Island where there was significant flooding.
  • Durham Seeking Nonprofit Applicants for Permanent Housing Funds
    DURHAM, N.C. - November 21, 2012 - (RealEstateRama) -- Durham affordable housing nonprofits serving chronically homeless individuals should take note that additional federal funding is available and that the City of Durham is seeking applicants for it

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Source: http://states.realestaterama.com/2012/11/22/congressman-al-green-sends-letter-to-the-department-of-housing-and-urban-development-as-well-as-the-department-of-justice-concerning-an-invidious-notice-posted-on-the-property-of-an-apartment-complex-ID021778.html

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Career Center Wraps Up First Career Roadmap Course for MBAs ...


Toni Della-Ratta

The F. David Fowler Career Center concluded the School?s first-ever, required Career Roadmap course for Global MBA students ? jump starting their job-search preparation with instruction on writing resumes, crafting LinkedIn profiles and handling interviews.

The 16-week course, which was taught to all 113 first-year GMBA students and wrapped up earlier this month, was aimed at not only improving students? knowledge of?job-search techniques and strategies, but helping them assess their skills and develop plans for managing their careers early in their MBA training.? It was taught by Career Center instructors.

A similar course was offered to undergraduates last year.? The MBA version kicked off this summer, before regular classes started.

?This was a very practical course,? said Toni Della-Ratta, the Center?s associate director of graduate career management services.? One obvious benefit, she said, is that the course provided a structure within which MBA students were required to write resumes and perform other job-search-related tasks that they might otherwise postpone until later in their course of study.

During the nine-part series, students conducted self-assessments; prepared written documents such as cover letters and resumes; developed plans to market themselves; and attended networking events and career fairs.? They used the tool Interview Stream to record themselves during mock interviews and sent the links to their coaches for assessment.

Social media was integrated into the course, with students receiving coaching on tailoring and presenting profiles on LinkedIn, the online professional network.

?Employers are actually hiring off of LinkedIn profiles,? said Della-Ratta.

One overall lesson the instructors tried to impart, she said,?is that today?s employers are increasingly looking for very specific skills, as opposed to hiring for?general business positions. That means students must carefully target themselves toward a particular industry, company or job that interests them.

?Many persons are coming back to get an MBA to change careers,? she said. ?What worked for them in the past might not work for them in their future.?

The Center has surveyed students on what they learned from the course, and their level of satisfaction.? Those results are being tabulated.

Posted by GWSB on November 20, 2012 | Filed under: Career Center News,GWSB News.

Source: http://atthecenterofitall.business.gwu.edu/2012/11/20/career-center-wraps-up-first-career-roadmap-course-for-mbas/

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Escapades in Cookery: Bad Food > No Food?

Matt Yglesias makes an interesting point about how, despite coffee snobs' (Matt said it first!) protestations to the contrary, Starbucks has on balance been a force for coffee progress in the US. As he puts it:

"The worst coffee shop or bookstore or whatever is the one that doesn't exist at all, it's only by bringing ideas to scale that you can achieve ubiquity."

There are many places whose markets are so small that its tough to support much diversity in product offerings and/or more specialized stores. Although these lower quality, mass produced options are inferior, they help to spread acceptance and build appreciation for the specialized goods (and services), which may ultimately lead consumers to explore and pursue higher quality versions of those goods. The spread of bagels across America is another example of this.

You gotta start somewhere, right?

But this got me thinking, what about the innumerable bad "Chinese" (Americanized-Chinese) restaurants all over America? Or bad "Thai"? Or bad "Japanese"? This hits closer to home for me. It's easier for me to accept the Bad Coffee > No Coffee argument since I rarely drink coffee. But is bad, super-Americanized Chinese food better than no Chinese food? I don't ever eat at Panda Express or Charlie Chang's--but coffee connoisseurs probably don't ever patronize Starbucks, either.

If we could see a definite trend toward Americans' appreciation and demand for better Chinese food, then I think I'd agree with the Bad Food > No Food argument. And honestly? I think we do see that trend, very slowly but surely. Though, there are many (most) who are satisfied with the dumbed-down Americanized versions of "exotic" cuisines.*

*And to be sure, Americanized-Chinese, in particular, has really evolved into its own thing at this point.

Source: http://escapadesincookery.blogspot.com/2012/11/bad-food-no-food.html

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Fighter loses by TKO: Vomiting (VIDEO)

Levi West has two losses in his professional career, but something tells me his second one will be more memorable. As shown on Inside MMA, West lost by technical knockout: vomiting. (It's the second fight mentioned in the short clip.)

The old wives tale advises swimmers to stay out of a pool for at least 30 minutes after eating. Perhaps it needs to be revised for fighters, as well.

Source: http://sports.yahoo.com/blogs/mma-cagewriter/fighter-loses-tko-vomiting-video-235121053--mma.html

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From Vegas to Macau to Toronto? | Pokerati

A study by UNLV?s International Gaming Institute concluded a resort complex featuring a hotel, casino, convention space and other entertainment amenities in the heart of Toronto could stimulate the economy of Canada?s largest city.

Instead of cannibalizing the market, the complex would spur growth for any surrounding businesses.

Meanwhile, the worldwide accounting firm Ernst & Young found that Toronto could collect almost $200 million a year from a casino complex in the form of tax revenues, on top of a one-time sale or lease of city-owned land.

So it wasn?t a surprise last week that Toronto city leaders, following the public release of the two reports, decided to ask residents if they favor a casino.

It?s also no wonder that Caesars Entertainment Corp. Senior Vice President Jan Jones and MGM Resorts Senior Vice President Alan Feldman are bumping into each other more often in Toronto than on the Strip.

Nevada?s biggest casino companies view Toronto as the industry?s next major battleground.

?It?s truly a potential destination we can?t ignore,? Jones said.

Earlier this year, the Ontario Lottery and Gaming Corp. announced plans to develop a single hotel-casino complex in Toronto. Government officials said the facility could generate $1 billion a year in gaming revenues.

Comparisons were immediately made between Toronto and Singapore.

Ernst & Young scaled back the revenue projections but still lauded the notion of a Toronto casino.

?It was noted that several characteristics of Toronto would make the city an attractive locale for international high rollers including the lack of taxes levied on gambling wins, the number of direct flights from Asian countries and the local demographics and family connections to Asia,? Ernst & Young officials wrote in the executive summary of its Commercial Casino in Toronto Study, which was researched on behalf of the city.

Singapore approved two casinos back in 2005, after much heated debate, as a means to drive tourism. Gaming was limited to a small portion of the two integrated resorts, but Singapore could surpass the Strip as the world?s second-largest gaming market behind Macau by the end of this year.

SINGAPORE MODEL

Toronto is following the Singapore model, and the debate is expected to be equally as furious. No casino will happen without the support of Toronto and its citizens.

Toronto Mayor Rob Ford backs the casino idea, but the Toronto city council has 43 members and their decision process is expected to stretch into next year.

?I don?t envy that task,? said Jones, a former two-term mayor of Las Vegas who oversaw a panel with five elected council members.

Ten days ago, Caesars released conceptual artist renderings of what a downtown Toronto casino complex might look like. Caesars is in partnership with Rock Gaming of Detroit, the company?s joint venture partner in the Horseshoe casinos in Cleveland, Cincinnati and Baltimore.

Jones said the Caesars project would be on Toronto?s downtown Front Street, and likened the complex to Harrah?s New Orleans, which is near that city?s French Quarter. Casino resorts of that caliber cost $1 billion to $2 billion to build.

?It?s all conceptual and at the end of the day, we would locate a casino where the city requests,? Jones said.

MGM Resorts, which jumped into the Toronto gaming debate early in the process, has championed Exhibition Place, a location outside of downtown that has support from several city leaders.

Canadian media reported in September than Jones and Feldman actually crossed paths between meetings at Toronto?s City Hall.

Meanwhile, Las Vegas Sands Corp. President Mike Leven, during the company?s third-quarter earnings conference call, said the casino operator chose a downtown site.

In August, Las Vegas Sands Chairman Sheldon Adelson had a private meeting with Toronto?s mayor.

?We don?t know where that project is going to go at the moment, but we?re ready to pursue it as soon as the project is released and our conditions are met,? Leven said. ?The return on investment is critical, particularly in the North American locations.?

Wynn Resorts Chairman Steve Wynn in October visited several potential casino sites, including the Toronto Convention Center and the Canadian National Exhibition grounds.

GAUGING ?CANNIBALIZATION?

The reports by Ernst & Young and the International Gaming Institute have only added fuel to what?s expected to be a heated competition.

The University of Nevada, Las Vegas study is the first of four the research team plans to conduct on the Toronto market on behalf of the Canadian Gaming Association, a nonprofit advocacy group. Other studies include the potential social costs of the casino, any impact the casino would have on problem gambling in the region, and the economic impact of a casino.

Bo Bernhard, executive director of the International Gaming Institute, said the school?s researchers wanted to study emerging gaming markets. He and Kahlil Philander reviewed research on casino gaming?s impact on other gaming and nongaming industries in the U.S. to determine any effects of ?cannibalization.?

Bernhard and Philander concluded a Toronto casino would not hurt nearby businesses or diminish lottery revenues.

?When the studies are applied to the Toronto situation, you have megaconvention facilities, a large hotel and tourists having lots of disposable income,? Bernhard said. ?They will venture out and spend that money in nearby locations.?

The Toronto area already has several forms of gaming, including lotteries, horse racing and a slot-machine casino at the Woodbine racetrack.

Ontario is home to a dozen small and midsized casinos, including Casino Niagara in Niagara Falls, and Caesars Windsor, which has been operated by Caesars Entertainment since 1998.

?There is minimal downside risk,? said Philander, who lived for a year in downtown Toronto while studying economics at the University of Toronto.

?Cannibalization is often claimed with respect to casinos but we could not find strong empirical evidence to support this argument,? Philander said.


Source: http://pokerati.com/2012/11/from-vegas-to-macau-to-toronto/

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Lego Lord of the Rings Blacksmith Designs Locations Guide

Our Lego Lord of the Rings Blacksmith Designs Locations Guide shows all the criteria necessary to collect all 50 Blacksmith Designs in the Wii, Xbox 360, PS3, PC, PS Vita, DS & 3DS game.

Goal: There are 50 Blacksmith Designs total to find, 30 of which are from the Middle-earth overworld and 20 from Story Mode missions. Note: From the 30 Mithril Items there are to build from the 30 Blacksmith Designs in the overworld, each object will cost a few Mithril Bricks to build at the Blacksmith. You can follow our locations guide for those too, it?s all listed here?

Index of Lego Lord of the Rings Guides:

Here?s how to find Blacksmith Designs in this guide for Lego Lord of the Rings.

Protip: Go and find the ?Fetch Quest Finder? Red Brick first. It?ll make it a lot easier to find all the Fetch Quest sidequests around you wherever you are, a reward for these involving a Blacksmith will be a Blacksmith Design.
You can either unlock this Red Brick using the EY4K32 cheat in the pause menu?s ?Extras? Enter Code section. Or find this Red Brick in Middle-earth open world by finishing the blacksmith tutorial mission in Bree village, by walking up to the Prancing Pony inn and talking to the hobbit who wants a Mithril Item made. And as you probably guessed, you need a Blacksmith Design from that Fetch Quest to craft such Mithril Items.

Below we?ve listed the Blacksmith Designs in the order you might find them in as you progress through the game. Take the following steps to unlock each one; where available.

Blacksmith Design #1: Mithril Shovel ? The first one you will unlock will be during the story mission in the town of Bree early in the game. It introduces this new feature and you make the Mithril Shovel.
Blacksmith Design #2 ? During the Pass of Caradhras mission, this one comes about 3/4th of the way into the mission. When you have to cross a lower path with Gimli or a hobbit, you will come to a ledge at the bottom of the screen. You will also hear the standard tingle noise when a collectible is nearby, so go out onto the ledge at the bottom of the screen and pick up the design.

[Work-In-Progress: We'll update this guide regularly when new Blacksmith Designs location info is discovered until it's 100% complete with all 50!]

Thanks for the (upcoming) unlock guide videos to Jeff.

Please check our at the top listed Lego Lord of the Rings guides for tips to find 100% of the collectibles.

If you have any questions, please comment below. If you have tips about Blacksmith Designs, we?ll give you credit for your discoveries! ? Thanks for visiting!

About the author

Ferry GroenendijkBy Ferry Groenendijk: He is the founder and editor of Video Games Blogger. He loved gaming from the moment he got a Nintendo with Super Mario Bros. on his 8th birthday. Learn more about him here and connect with him on Twitter, Facebook and at Google+.


Source: http://www.videogamesblogger.com/2012/11/18/lego-lord-of-the-rings-blacksmith-designs-locations-guide.htm

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Review: Bair writes bio of artist Saul Steinberg - KansasCity.com

"Saul Steinberg: A Biography" (Doubleday/Nan A. Talese), by Deirdre Bair

When New Yorker cartoonist Saul Steinberg was honored in 1974 by the American Academy of Arts and Letters, the architect Philip Johnson puzzled out loud over how best to describe him.Although Steinberg was about to receive the gold medal for graphic art, wasn't he also a satirist, a painter, a humorist and an architect? After bemoaning the seeming necessity of putting artists into categories, Johnson concluded by saying, "We cannot pigeonhole Saul Steinberg."Now Deirdre Bair, the author of well-regarded books about Samuel Beckett, Carl Jung and Simone de Beauvoir, has taken stock of this wildly inventive and original artist in a 600-page volume that marks the first comprehensive biography of Steinberg since he died in 1999 at age 84.Steinberg was happy to call himself a writer who draws. An architect by training, he delighted in drawing fantastic buildings and cityscapes, including his iconic "View of the World From Ninth Avenue," the New Yorker cover endlessly parodied since it was published in 1976.Steeped in the Dada, surrealist and cubist art movements of his youth in Romania and later Italy, Steinberg never lost his off-kilter, intentionally childlike and absurdist view of the world. He peopled his imaginary worlds with animated letters, numbers and punctuation marks; with battle-ax women patterned on his domineering mother; and with a profusion of animals and objects that were his own personal totems yet which resonated with a wide swath of the public.Even as a penniless Jewish refugee awaiting permission to enter the U.S. at the start of World War II, Steinberg found success selling his offbeat cartoons to the New Yorker. Once he was finally settled in New York, nothing could stop his rapid rise to the pinnacle of the art world, not even his hypochondria, anxiety and lifelong depression.In "Saul Steinberg: A Biography," readers learn that Steinberg was a man of insatiable appetites: for women, books, objects and travel. Bair gets bogged down at times in the details - the endless parties and dinners with art world celebrities; the haggling over commissions and negotiations with publishers; his apartment and studio renovations; and the bitter fights with his lovers. But overall she has done an excellent job of trying to answer the question that perplexed even Steinberg's ex-wife and lifelong friend Hedda Sterne when she considered his work: "Where did this come from?"---Online:http://www.deirdrebair.com/index.html

Source: http://www.kansascity.com/2012/11/20/3926651/review-bair-writes-bio-of-artist.html

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Can breast cancer cells' reaction to cancer drugs be predicted?

Can breast cancer cells' reaction to cancer drugs be predicted? [ Back to EurekAlert! ] Public release date: 19-Nov-2012
[ | E-mail | Share Share ]

Contact: Samuel Kaski
samuel.kaski@hiit.fi
358-503-058-694
Aalto University

Yes, Finnish researchers discover

The answer is yes. Finnish researchers have developed a triumphant solution for predicting responses of breast cancer cells to a set of cancer drugs. The prediction is based on the genomic profiles of the cancer cells. Harnessing genomic profiles of cells in choosing the best treatment is considered the holy grail of personalised medicine.

The team led by Professor Samuel Kaski from Helsinki institute of Information Technology (HIIT), a joint research centre of Aalto University and University of Helsinki, Finland, presented its winning solution at the DREAM 2012 conference on November 13 in San Francisco. The team's solution outperformed 47 other teams in the prediction challenge world-wide.

Computational methods integrate multiple views of the genomic profile of cancer cells

It is well known that drug therapies may effectively kill cancer cells in one patient, but not in another patient suffering from the same type of cancer. However, the molecular determinants underlying the differences in drug response have not so far been sufficiently understood.

  • The goal in computational personalised medicine is to develop models which predict drug sensitivity of cells from their genomic profiles, Kaski explains.

The organisers of the NCI-Dream challenge provided data of breast cancer cells for the training of computational sensitivity prediction models. They evaluated the participants' models on test measurements of drugs that were unknown to the participants.

As in most current biomedical experiments, several types of measurements had been collected on the cancer cells: activity of genes, epigenetics, and genetic profiles. The key problem was to optimally combine the complementary "views" that the different measurements yield.

  • We had been developing new machine learning methods for these 'multi-view' problems, which occur in many fields, and they gave us a flying start, tells Kaski.
  • The challenge was a great additional opportunity for us to put our heads together. People with different backgrounds presented different views on the problem and brought in their own expertise and experience to improve the integrated solution, says HIIT researcher Dr Elisabeth Georgii.

Although the result is still far from clinical applicability, computational personalised medicine has taken an encouraging, prize-winning step forward.

###

The team led by Professor Samuel Kaski from HIIT, a joint research centre of Aalto University and University of Helsinki, presented its winning solution at the DREAM 2012 conference on November 13 in San Francisco. The team's solution outperformed 47 other teams in the prediction challenge.

The team participated in the seventh annual DREAM competition http://www.the-dream-project.org/ organised by the U.S. National Cancer Institute (NCI) and The Dialogue for Reverse Engineering Assessments and Methods (DREAM). Their challenges crowd-source highly demanding scientific problems to top research teams around the world. The best solution will be published in a leading journal.


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Can breast cancer cells' reaction to cancer drugs be predicted? [ Back to EurekAlert! ] Public release date: 19-Nov-2012
[ | E-mail | Share Share ]

Contact: Samuel Kaski
samuel.kaski@hiit.fi
358-503-058-694
Aalto University

Yes, Finnish researchers discover

The answer is yes. Finnish researchers have developed a triumphant solution for predicting responses of breast cancer cells to a set of cancer drugs. The prediction is based on the genomic profiles of the cancer cells. Harnessing genomic profiles of cells in choosing the best treatment is considered the holy grail of personalised medicine.

The team led by Professor Samuel Kaski from Helsinki institute of Information Technology (HIIT), a joint research centre of Aalto University and University of Helsinki, Finland, presented its winning solution at the DREAM 2012 conference on November 13 in San Francisco. The team's solution outperformed 47 other teams in the prediction challenge world-wide.

Computational methods integrate multiple views of the genomic profile of cancer cells

It is well known that drug therapies may effectively kill cancer cells in one patient, but not in another patient suffering from the same type of cancer. However, the molecular determinants underlying the differences in drug response have not so far been sufficiently understood.

  • The goal in computational personalised medicine is to develop models which predict drug sensitivity of cells from their genomic profiles, Kaski explains.

The organisers of the NCI-Dream challenge provided data of breast cancer cells for the training of computational sensitivity prediction models. They evaluated the participants' models on test measurements of drugs that were unknown to the participants.

As in most current biomedical experiments, several types of measurements had been collected on the cancer cells: activity of genes, epigenetics, and genetic profiles. The key problem was to optimally combine the complementary "views" that the different measurements yield.

  • We had been developing new machine learning methods for these 'multi-view' problems, which occur in many fields, and they gave us a flying start, tells Kaski.
  • The challenge was a great additional opportunity for us to put our heads together. People with different backgrounds presented different views on the problem and brought in their own expertise and experience to improve the integrated solution, says HIIT researcher Dr Elisabeth Georgii.

Although the result is still far from clinical applicability, computational personalised medicine has taken an encouraging, prize-winning step forward.

###

The team led by Professor Samuel Kaski from HIIT, a joint research centre of Aalto University and University of Helsinki, presented its winning solution at the DREAM 2012 conference on November 13 in San Francisco. The team's solution outperformed 47 other teams in the prediction challenge.

The team participated in the seventh annual DREAM competition http://www.the-dream-project.org/ organised by the U.S. National Cancer Institute (NCI) and The Dialogue for Reverse Engineering Assessments and Methods (DREAM). Their challenges crowd-source highly demanding scientific problems to top research teams around the world. The best solution will be published in a leading journal.


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ScienceDaily: Latest Science News

ScienceDaily: Latest Science Newshttp://www.sciencedaily.com/news/ Breaking science news and articles on global warming, extrasolar planets, stem cells, bird flu, autism, nanotechnology, dinosaurs, evolution -- the latest discoveries in astronomy, anthropology, biology, chemistry, climate and environment, computers, engineering, health and medicine, math, physics, psychology, technology, and more -- from the world's leading universities and research organizations.en-usMon, 19 Nov 2012 20:12:55 ESTMon, 19 Nov 2012 20:12:55 EST60ScienceDaily: Latest Science Newshttp://www.sciencedaily.com/images/logosmall.gifhttp://www.sciencedaily.com/news/ For more science articles, visit ScienceDaily.Hubble traps galactic fireflieshttp://www.sciencedaily.com/releases/2012/11/121119174215.htm A remote sensing instrument that will peer into the ultraviolet to offer clues to how Mars might have lost its atmosphere has arrived at Lockheed Martin for integration into NASA's Mars Atmosphere and Volatile EvolutioN (MAVEN) spacecraft.Mon, 19 Nov 2012 17:42:42 ESThttp://www.sciencedaily.com/releases/2012/11/121119174215.htmInstrument delivered for NASA's upcoming Mars missionhttp://www.sciencedaily.com/releases/2012/11/121119173923.htm A remote sensing instrument that will peer into the ultraviolet to offer clues to how Mars might have lost its atmosphere has arrived at Lockheed Martin for integration into NASA's Mars Atmosphere and Volatile EvolutioN (MAVEN) spacecraft.Mon, 19 Nov 2012 17:39:39 ESThttp://www.sciencedaily.com/releases/2012/11/121119173923.htmAh, that new car smell: NASA technology protects spacecraft from outgassed molecular contaminantshttp://www.sciencedaily.com/releases/2012/11/121119173754.htm Outgassing -- the physical process that creates that oh-so-alluring new car smell -- isn't healthy for humans and, as it turns out, not particularly wholesome for sensitive satellite instruments, either. But a team of NASA engineers has created a new way to protect those instruments from its ill effects.Mon, 19 Nov 2012 17:37:37 ESThttp://www.sciencedaily.com/releases/2012/11/121119173754.htmWhat goes down must come back up: Effects of 2010-11 La Ni?a on global sea levelhttp://www.sciencedaily.com/releases/2012/11/121119172938.htm In 2010-11, global sea level fell nearly a quarter inch. But, when it comes to long-term sea level, what comes down must eventually come back up.Mon, 19 Nov 2012 17:29:29 ESThttp://www.sciencedaily.com/releases/2012/11/121119172938.htmSmoking in pregnancy tied to lower reading scoreshttp://www.sciencedaily.com/releases/2012/11/121119163703.htm Researchers have found that children born to mothers who smoked more than one pack per day during pregnancy struggled on tests designed to measure how accurately a child reads aloud and comprehends what they read.Mon, 19 Nov 2012 16:37:37 ESThttp://www.sciencedaily.com/releases/2012/11/121119163703.htmPotential cause of Parkinson's disease identifiedhttp://www.sciencedaily.com/releases/2012/11/121119163659.htm Scientists have pinpointed a key factor controlling damage to brain cells in a mouse model of Parkinson's disease. The discovery could lead to new targets for Parkinson's that may be useful in preventing the actual condition.Mon, 19 Nov 2012 16:36:36 ESThttp://www.sciencedaily.com/releases/2012/11/121119163659.htmNew tumor tracking technique may improve outcomes for lung cancer patientshttp://www.sciencedaily.com/releases/2012/11/121119163506.htm Researchers have shown that a real-time tracking technique can better predict and track tumor motion and deliver higher levels of radiation to lung cancer patients and others with moving tumor targets, and also successfully be implemented into existing clinical equipment.Mon, 19 Nov 2012 16:35:35 ESThttp://www.sciencedaily.com/releases/2012/11/121119163506.htmStorm surge barriers for Manhattan could worsen effects on nearby areas: Other options proposedhttp://www.sciencedaily.com/releases/2012/11/121119163504.htm The flooding in New York and New Jersey caused by Superstorm Sandy prompted calls from Gov. Andrew Cuomo and other officials to consider building storm surge barriers to protect Lower Manhattan from future catastrophes. But, such a strategy could make things even worse for outlying areas that were hit hard by the hurricane, such as Staten Island, the New Jersey Shore and Long Island's South Shore, a City College of New York landscape architecture professor warns.Mon, 19 Nov 2012 16:35:35 ESThttp://www.sciencedaily.com/releases/2012/11/121119163504.htmMars formed from similar building blocks to that of Earth, reveals study of Martian meteoriteshttp://www.sciencedaily.com/releases/2012/11/121119163500.htm A team of scientists studied the hydrogen in water from the Martian interior and found that Mars formed from similar building blocks to that of Earth, but that there were differences in the later evolution of the two planets. This implies that terrestrial planets, including Earth, have similar water sources.Mon, 19 Nov 2012 16:35:35 ESThttp://www.sciencedaily.com/releases/2012/11/121119163500.htm'Dark energy' -- Life beneath the seafloor: Scientists present recent findings on the subsurface biospherehttp://www.sciencedaily.com/releases/2012/11/121119163458.htm Scientists affiliated with the National Science Foundation (NSF) Center for Dark Energy Biosphere Investigations (C-DEBI) will discuss recent progress in understanding life beneath the seafloor at the American Geophysical Union (AGU) fall meeting, held in San Francisco from Dec. 3-7, 2012. Once considered a barren plain dotted with hydrothermal vents, the seafloor and the crust beneath it are humming with microbial life -- with "dark energy". Once considered a barren plain dotted with hydrothermal vents, the seafloor and the crust beneath it are humming with microbial life -- with "dark energy,"Mon, 19 Nov 2012 16:34:34 ESThttp://www.sciencedaily.com/releases/2012/11/121119163458.htmElectronic visits offer accurate diagnoses, may lead to overprescribing of antibioticshttp://www.sciencedaily.com/releases/2012/11/121119163337.htm One of the first studies to compare patients who see their doctors in person to those who receive care through the Internet, known as an e-visit, underscores both the promise and the pitfalls of this technology. Researchers found that patients who used e-visits for sinusitis and urinary tract infections (UTIs) were no more likely to need follow-up care than those who saw doctors in person.Mon, 19 Nov 2012 16:33:33 ESThttp://www.sciencedaily.com/releases/2012/11/121119163337.htmHigh Vitamin D levels in pregnancy may protect mother more than baby against multiple sclerosishttp://www.sciencedaily.com/releases/2012/11/121119163331.htm Pregnant women who have higher levels of vitamin D in their blood may have a lower risk of developing multiple sclerosis than women with lower levels, while their babies may not see the same protective effect, according to a new study.Mon, 19 Nov 2012 16:33:33 ESThttp://www.sciencedaily.com/releases/2012/11/121119163331.htmMultiple sclerosis ?immune exchange? between brain and blood is uncoveredhttp://www.sciencedaily.com/releases/2012/11/121119163301.htm DNA sequences obtained from a handful of patients with multiple sclerosis have revealed the existence of an ?immune exchange? that allows the disease-causing cells to move in and out of the brain.Mon, 19 Nov 2012 16:33:33 ESThttp://www.sciencedaily.com/releases/2012/11/121119163301.htmFailed explosions explain most peculiar supernovaehttp://www.sciencedaily.com/releases/2012/11/121119163251.htm Supercomputer simulations have revealed that a type of oddly dim, exploding star is probably a class of duds?one that could nonetheless throw new light on the mysterious nature of dark energy.Mon, 19 Nov 2012 16:32:32 ESThttp://www.sciencedaily.com/releases/2012/11/121119163251.htmAstronomers pin down origins of 'mile markers' for expansion and acceleration of universehttp://www.sciencedaily.com/releases/2012/11/121119163248.htm A study using a unique new instrument on the world's largest optical telescope has revealed the likely origins of especially bright supernovae that astronomers use as easy-to-spot "mile markers" to measure the expansion and acceleration of the universe.Mon, 19 Nov 2012 16:32:32 ESThttp://www.sciencedaily.com/releases/2012/11/121119163248.htmLava dots: Hollow, soft-shelled quantum dots createdhttp://www.sciencedaily.com/releases/2012/11/121119151322.htm Serendipity proved to be a key ingredient for newly created nanoparticles. The new "lava dot" particles were discovered accidentally when researchers stumbled upon a way to use molten droplets of metal salt to make hollow, coated versions of a nanotech staple called quantum dots.Mon, 19 Nov 2012 15:13:13 ESThttp://www.sciencedaily.com/releases/2012/11/121119151322.htmNew energy technologies promise brighter futurehttp://www.sciencedaily.com/releases/2012/11/121119151320.htm Creative new technologies could change our sources of energy, change our use of energy, and change our lives.Mon, 19 Nov 2012 15:13:13 ESThttp://www.sciencedaily.com/releases/2012/11/121119151320.htmAfter 121 years, identification of 'grave robber' fossil solves a paleontological enigmahttp://www.sciencedaily.com/releases/2012/11/121119151318.htm Researchers have resolved the evolutionary relationships of Necrolestes patagonensis, a paleontological riddle for more than 100 years. Researchers have correctly placed the strange 16-million-year-old Necrolestes in the mammal evolutionary tree, unexpectedly moving forward the endpoint for the fossil's evolutionary lineage by 45 million years and showing that this family of mammals survived the extinction event that marked the end of the Age of Dinosaurs.Mon, 19 Nov 2012 15:13:13 ESThttp://www.sciencedaily.com/releases/2012/11/121119151318.htmHappy youngsters more likely to grow into wealthy adults, study findshttp://www.sciencedaily.com/releases/2012/11/121119151316.htm The first in-depth investigation of whether youthful happiness leads to greater wealth in later life reveals that, even allowing for other influences, happy adolescents are likely to earn more money as adults.Mon, 19 Nov 2012 15:13:13 ESThttp://www.sciencedaily.com/releases/2012/11/121119151316.htm'Different kind of stem cell' possesses attributes favoring regenerative medicinehttp://www.sciencedaily.com/releases/2012/11/121119151314.htm New and powerful cells first created in the laboratory a year ago constitute a new stem-like state of adult epithelial cells with attributes that may make regenerative medicine truly possible. Researchers report that these new stem-like cells do not express the same genes as embryonic stem cells and induced pluripotent stem cells (iPSCs) do. That explains why they don't produce tumors when they grow in the laboratory, as the other stem cells do, and why they are stable, producing the kind of cells researchers want them to.Mon, 19 Nov 2012 15:13:13 ESThttp://www.sciencedaily.com/releases/2012/11/121119151314.htmEvidence of a 'mid-life crisis' in great apeshttp://www.sciencedaily.com/releases/2012/11/121119151311.htm Chimpanzees and orangutans can experience a mid-life crisis just like humans, a study suggests.Mon, 19 Nov 2012 15:13:13 ESThttp://www.sciencedaily.com/releases/2012/11/121119151311.htmBody may be able to 'coach' transplanted stem cells to differentiate appropriatelyhttp://www.sciencedaily.com/releases/2012/11/121119151308.htm Pluripotent stem cells are nature's double-edged sword. Because they can develop into a dizzying variety of cell types and tissues, they are a potentially invaluable therapeutic resource. However, that same developmental flexibility can lead to dangerous tumors called teratomas if the stem cells begin to differentiate out of control in the body.Mon, 19 Nov 2012 15:13:13 ESThttp://www.sciencedaily.com/releases/2012/11/121119151308.htmHow yeast protein breaks up amyloid fibrils and disordered protein clumpshttp://www.sciencedaily.com/releases/2012/11/121119151220.htm Hsp104, an enzyme from yeast, breaks up both amyloid fibrils and disordered clumps. For stable amyloid-type structures, Hsp104 needs all six of its subunits, which together make a hexamer, to pull the clumps apart. By contrast, for amorphous, non-amyloid clumps, Hsp104 required only one of its six subunits.Mon, 19 Nov 2012 15:12:12 ESThttp://www.sciencedaily.com/releases/2012/11/121119151220.htmExperimental drug improves memory in mice with multiple sclerosishttp://www.sciencedaily.com/releases/2012/11/121119151218.htm Researchers report the successful use of a form of MRI to identify what appears to be a key biochemical marker for cognitive impairment in the brains of people with multiple sclerosis (MS). In follow-up experiments on mice with a rodent form of MS, researchers were able to use an experimental compound to manipulate that same marker and dramatically improve learning and memory.Mon, 19 Nov 2012 15:12:12 ESThttp://www.sciencedaily.com/releases/2012/11/121119151218.htmHold the ice: Chemists reveal behavior of antifreeze moleculeshttp://www.sciencedaily.com/releases/2012/11/121119151216.htm Chemists have discovered a family of anti-freeze molecules that prevent ice formation when water temperatures drop below 32 degrees Fahrenheit. Their findings may lead to new methods for improving food storage and industrial products.Mon, 19 Nov 2012 15:12:12 ESThttp://www.sciencedaily.com/releases/2012/11/121119151216.htmSuper-efficient solar-energy technology: ?Solar steam? so effective it can make steam from icy cold waterhttp://www.sciencedaily.com/releases/2012/11/121119140627.htm Scientists have unveiled a revolutionary new technology that uses nanoparticles to convert solar energy directly into steam. The new "solar steam" method is so effective it can even produce steam from icy cold water. The technology's inventors said they expect it will first be used in sanitation and water-purification applications in the developing world.Mon, 19 Nov 2012 14:06:06 ESThttp://www.sciencedaily.com/releases/2012/11/121119140627.htmEmbattled childhoods may be the real trauma for soldiers with PTSDhttp://www.sciencedaily.com/releases/2012/11/121119140625.htm New research on posttraumatic stress disorder in soldiers challenges popular assumptions about the origins and trajectory of PTSD, providing evidence that traumatic experiences in childhood - not combat - may predict which soldiers develop the disorder.Mon, 19 Nov 2012 14:06:06 ESThttp://www.sciencedaily.com/releases/2012/11/121119140625.htmAstrophysicists identify a 'super-Jupiter' around massive starhttp://www.sciencedaily.com/releases/2012/11/121119140621.htm Astrophysicists have discovered a 'super-Jupiter' around the massive star Kappa Andromedae. It represents the first new imaged exoplanet system in almost four years, has a mass about 13 times that of Jupiter and an orbit somewhat larger than Neptune's. The star around which the planet orbits has a mass 2.5 times that of the Sun, making it the highest mass star to ever host a directly observed planet.Mon, 19 Nov 2012 14:06:06 ESThttp://www.sciencedaily.com/releases/2012/11/121119140621.htmHuman brain, Internet, and cosmology: Similar laws at work?http://www.sciencedaily.com/releases/2012/11/121119140545.htm The structure of the universe and the laws that govern its growth may be more similar than previously thought to the structure and growth of the human brain and other complex networks, such as the Internet or a social network of trust relationships between people, according to a new article.Mon, 19 Nov 2012 14:05:05 ESThttp://www.sciencedaily.com/releases/2012/11/121119140545.htmGreenland's viking settlers gorged on sealshttp://www.sciencedaily.com/releases/2012/11/121119132311.htm Greenland's viking settlers, the Norse, disappeared suddenly and mysteriously from Greenland about 500 years ago. Natural disasters, climate change and the inability to adapt have all been proposed as theories to explain their disappearance. But now a Danish-Canadian research team has demonstrated the Norse society did not die out due to an inability to adapt to the Greenlandic diet: an isotopic analysis of their bones shows they ate plenty of seals.Mon, 19 Nov 2012 13:23:23 ESThttp://www.sciencedaily.com/releases/2012/11/121119132311.htmClues to cause of hydrogen embrittlement in metals: Findings could guide design of new embrittlement-resistant materialshttp://www.sciencedaily.com/releases/2012/11/121119132309.htm Hydrogen can easily dissolve and migrate within metals to make these otherwise ductile materials brittle and more prone to failures. Now, researchers have shown that the physics of hydrogen embrittlement may be rooted in how hydrogen modifies material behaviors at the nanoscale. Scientists have now presented a model that can accurately predict the occurrence of hydrogen embrittlement.Mon, 19 Nov 2012 13:23:23 ESThttp://www.sciencedaily.com/releases/2012/11/121119132309.htmNeed to filter water? Fight infection? Just open package, mix polymershttp://www.sciencedaily.com/releases/2012/11/121119132305.htm Researchers have developed what they call a one-size-fits-all polymer system that can be fabricated and then specialized to perform healing functions ranging from fighting infection to wound healing.Mon, 19 Nov 2012 13:23:23 ESThttp://www.sciencedaily.com/releases/2012/11/121119132305.htmNew species literally spend decades on the shelfhttp://www.sciencedaily.com/releases/2012/11/121119132226.htm Many of the world's most unfamiliar species are just sitting around on museum shelves collecting dust. That's according to a new report showing that it takes more than 20 years on average before a species, newly collected, will be described.Mon, 19 Nov 2012 13:22:22 ESThttp://www.sciencedaily.com/releases/2012/11/121119132226.htmGenetic factor holds key to blood vessel healthhttp://www.sciencedaily.com/releases/2012/11/121119114300.htm Researchers have identified a genetic factor that prevents blockages from forming in blood vessels, a discovery that could lead to new therapies for cardiovascular diseases. Researchers found that a shortage of the genetic factor KLF4, which regulates endothelial cells lining the interior of blood vessels, makes the lining more prone to the buildup of plaque and fat deposits. Further, the deficiency made the blood vessel more susceptible to clot formation.Mon, 19 Nov 2012 11:43:43 ESThttp://www.sciencedaily.com/releases/2012/11/121119114300.htm3-D light switch for the brain: Device may help treat Parkinson's, epilepsy; aid understanding of consciousnesshttp://www.sciencedaily.com/releases/2012/11/121119114249.htm A new tool for neuroscientists delivers a thousand pinpricks of light to individual neurons in the brain. The new 3-D "light switch", created by biologists and engineers, could one day be used as a neural prosthesis that could treat conditions such as Parkinson's and epilepsy by using gene therapy to turn individual brain cells on and off with light.Mon, 19 Nov 2012 11:42:42 ESThttp://www.sciencedaily.com/releases/2012/11/121119114249.htmInvisibility cloaking to shield floating objects from waveshttp://www.sciencedaily.com/releases/2012/11/121119104529.htm A new approach to invisibility cloaking may one day be used at sea to shield floating objects ? such as oil rigs and ships ? from rough waves. Unlike most other cloaking techniques that rely on transformation optics, this one is based on the influence of the ocean floor?s topography on the various ?layers? of ocean water. At the American Physical Society?s (APS) Division of Fluid Dynamics (DFD) meeting, being held November 18-20, 2012, in San Diego, Calif., Reza Alam, assistant professor of mechanical engineering at the University of California, Berkeley, will describe how the variation of density in ocean water can be used to cloak floating objects against incident surface waves.Mon, 19 Nov 2012 10:45:45 ESThttp://www.sciencedaily.com/releases/2012/11/121119104529.htmSound bullets in waterhttp://www.sciencedaily.com/releases/2012/11/121119104527.htm Sound waves are commonly used in applications ranging from ultrasound imaging to hyperthermia therapy, in which high temperatures are induced, for example, in tumors to destroy them. In 2010, researchers developed a nonlinear acoustic lens that can focus high-amplitude pressure pulses into compact ?sound bullets.? In that initial work, the scientists demonstrated how sound bullets form in solids. Now, they have done themselves one better, creating a device that can form and control those bullets in water.Mon, 19 Nov 2012 10:45:45 ESThttp://www.sciencedaily.com/releases/2012/11/121119104527.htmOwls' ability to fly in acoustic stealth provides clues to mitigating conventional aircraft noisehttp://www.sciencedaily.com/releases/2012/11/121119104525.htm Owls have the uncanny ability to fly silently, relying on specialized plumage to reduce noise so they can hunt in acoustic stealth. Researchers are studying the owl?s wing structure to better understand how it mitigates noise so they can apply that information to the design of conventional aircraft.Mon, 19 Nov 2012 10:45:45 ESThttp://www.sciencedaily.com/releases/2012/11/121119104525.htmMosquitos fail at flight in heavy fog, though heavy rain doesn't faze themhttp://www.sciencedaily.com/releases/2012/11/121119104522.htm Mosquitos have the remarkable ability to fly in clear skies as well as in rain, shrugging off impacts from raindrops more than 50 times their body mass. But just like modern aircraft, mosquitos also are grounded when the fog thickens.Mon, 19 Nov 2012 10:45:45 ESThttp://www.sciencedaily.com/releases/2012/11/121119104522.htmWe're in this together: A pathbreaking investigation into the evolution of cooperative behaviorhttp://www.sciencedaily.com/releases/2012/11/121119094629.htm The origins of cooperative behavior are not altruism, but mutual interest, according to a new study.Mon, 19 Nov 2012 09:46:46 ESThttp://www.sciencedaily.com/releases/2012/11/121119094629.htmBaBar experiment confirms time asymmetry: Time's quantum arrow has a preferred direction, new analysis showshttp://www.sciencedaily.com/releases/2012/11/121119094627.htm Digging through nearly 10 years of data from billions of BaBar particle collisions, researchers found that certain particle types change into one another much more often in one way than they do in the other, a violation of time reversal symmetry and confirmation that some subatomic processes have a preferred direction of time.Mon, 19 Nov 2012 09:46:46 ESThttp://www.sciencedaily.com/releases/2012/11/121119094627.htmMore female board directors add up to improved sustainability performancehttp://www.sciencedaily.com/releases/2012/11/121119094625.htm As a corporate responsibility consultant, one expert publicly criticized Apple's recent appointment of another man to an already all-male executive team. New research goes one step further, indicating that the number of women on a corporate board correlates with a firm's sustainability performance.Mon, 19 Nov 2012 09:46:46 ESThttp://www.sciencedaily.com/releases/2012/11/121119094625.htmInpatient sleeping drug quadrupled fall riskhttp://www.sciencedaily.com/releases/2012/11/121119094623.htm A drug commonly prescribed to help patients sleep in hospitals has been associated with an increased risk of falls, according to a new study.Mon, 19 Nov 2012 09:46:46 ESThttp://www.sciencedaily.com/releases/2012/11/121119094623.htmCertain jobs linked to increased breast cancer riskhttp://www.sciencedaily.com/releases/2012/11/121119094512.htm Is there a link between the risk of breast cancer and the working environment? A new study provides further evidence on this previously neglected research topic, confirming that certain occupations do pose a higher risk of breast cancer than others, particularly those that expose the worker to potential carcinogens and endocrine disrupters.Mon, 19 Nov 2012 09:45:45 ESThttp://www.sciencedaily.com/releases/2012/11/121119094512.htmBreast cancer cells' reaction to cancer drugs can be predicted, study suggestshttp://www.sciencedaily.com/releases/2012/11/121119094510.htm Can breast cancer cells? reaction to cancer drugs be predicted? The answer is yes. Researchers have developed a solution for predicting responses of breast cancer cells to a set of cancer drugs. The prediction is based on the genomic profiles of the cancer cells. Harnessing genomic profiles of cells in choosing the best treatment is considered the holy grail of personalized medicine.Mon, 19 Nov 2012 09:45:45 ESThttp://www.sciencedaily.com/releases/2012/11/121119094510.htmScientists pioneer method to predict environmental collapsehttp://www.sciencedaily.com/releases/2012/11/121119093853.htm Scientists are pioneering a technique to predict when an ecosystem is likely to collapse, which may also have potential for foretelling crises in agriculture, fisheries or even social systems. The researchers have applied a mathematical model to a real world situation, the environmental collapse of a lake in China, to help prove a theory which suggests an ecosystem 'flickers,' or fluctuates dramatically between healthy and unhealthy states, shortly before its eventual collapse.Mon, 19 Nov 2012 09:38:38 ESThttp://www.sciencedaily.com/releases/2012/11/121119093853.htmA more peaceful world awaits, statistical analysis suggestshttp://www.sciencedaily.com/releases/2012/11/121119093846.htm Statistical analyses show that the world will be more peaceful in the future. In about 40 years only half as many countries will be in conflict. The decrease will be greatest in the Middle East, a statistical model suggests.Mon, 19 Nov 2012 09:38:38 ESThttp://www.sciencedaily.com/releases/2012/11/121119093846.htmPain medication addiction reaching epidemic levelhttp://www.sciencedaily.com/releases/2012/11/121119093654.htm Addiction to pain medication is creating new challenges for physicians. Would you believe -- hydrocodone was the most prescribed drug in America in 2011?Mon, 19 Nov 2012 09:36:36 ESThttp://www.sciencedaily.com/releases/2012/11/121119093654.htmOverwhelming public support for whistleblowershttp://www.sciencedaily.com/releases/2012/11/121118203536.htm New research shows 4 out of 5 Britons think that people should be supported for revealing serious wrongdoing, even if it means revealing inside information. However, under half of the respondents (47%) thought whistleblowing is an acceptable thing to do in our society. Hence, people think society is less supportive of it than it should be.Sun, 18 Nov 2012 20:35:35 ESThttp://www.sciencedaily.com/releases/2012/11/121118203536.htmMinority report: Insight into subtle genomic differences among our own cellshttp://www.sciencedaily.com/releases/2012/11/121118141530.htm Scientists have demonstrated that induced pluripotent stem cells -- the embryonic-stem-cell look-alikes whose discovery a few years ago won this year's Nobel Prize in medicine -- are not as genetically unstable as was thought.Sun, 18 Nov 2012 14:15:15 ESThttp://www.sciencedaily.com/releases/2012/11/121118141530.htmOptogenetics illuminates pathways of motivation through brainhttp://www.sciencedaily.com/releases/2012/11/121118141528.htm Bioengineers have isolated the neurons that carry split-second decisions to act from the higher brain to the brain stem. In doing so, they have provided insight into the causes of severe brain disorders such as depression.Sun, 18 Nov 2012 14:15:15 ESThttp://www.sciencedaily.com/releases/2012/11/121118141528.htmSkin cells reveal DNA's genetic mosaichttp://www.sciencedaily.com/releases/2012/11/121118141524.htm The prevailing wisdom has been that every cell in the body contains identical DNA. However, a new study of stem cells derived from the skin has found that genetic variations are widespread in the body's tissues, a finding with profound implications for genetic screening.Sun, 18 Nov 2012 14:15:15 ESThttp://www.sciencedaily.com/releases/2012/11/121118141524.htmScientists selectively repress immune system: New treatment to combat autoimmune disease in mouse modelhttp://www.sciencedaily.com/releases/2012/11/121118141522.htm In a mouse model of multiple sclerosis (MS), researchers have developed innovative technology to selectively inhibit the part of the immune system responsible for attacking myelin -- the insulating material that encases nerve fibers and facilitates electrical communication between brain cells.Sun, 18 Nov 2012 14:15:15 ESThttp://www.sciencedaily.com/releases/2012/11/121118141522.htmLeap forward in brain-controlled computer cursors: New algorithm greatly improves speed and accuracyhttp://www.sciencedaily.com/releases/2012/11/121118141520.htm Researchers have designed the fastest, most accurate algorithm yet for brain-implantable prosthetic systems that can help disabled people maneuver computer cursors with their thoughts. The algorithm's speed, accuracy and natural movement approach those of a real arm, and the system avoids the long-term performance degradations of earlier technologies.Sun, 18 Nov 2012 14:15:15 ESThttp://www.sciencedaily.com/releases/2012/11/121118141520.htmBreakthrough nanoparticle halts multiple sclerosis in mice, offers hope for other immune-related diseaseshttp://www.sciencedaily.com/releases/2012/11/121118141516.htm In a breakthrough for nanotechnology and multiple sclerosis (MS), a biodegradable nanoparticle delivers an antigen that tricks the immune system and halts MS in mice. The approach, the first that doesn't suppress the immune system, is being tested in a clinical trial for MS patients, but with white blood cells delivering the antigen. The nanoparticle is an easier, cheaper option and can be used in other immune-related diseases including Type 1 diabetes, food and airway allergies.Sun, 18 Nov 2012 14:15:15 ESThttp://www.sciencedaily.com/releases/2012/11/121118141516.htmLikely basis of birth defect causing premature skull closure in infants identifiedhttp://www.sciencedaily.com/releases/2012/11/121118141432.htm Geneticists, pediatricians, surgeons and epidemiologists have identified two areas of the human genome associated with the most common form of non-syndromic craniosynostosis premature closure of the bony plates of the skull.Sun, 18 Nov 2012 14:14:14 ESThttp://www.sciencedaily.com/releases/2012/11/121118141432.htmCall to modernize antiquated climate negotiationshttp://www.sciencedaily.com/releases/2012/11/121118141430.htm The?structure and processes of United Nations climate negotiations are "antiquated", unfair and obstruct attempts to reach agreements, according to new research.Sun, 18 Nov 2012 14:14:14 ESThttp://www.sciencedaily.com/releases/2012/11/121118141430.htmWomen in congress outperform men on some measureshttp://www.sciencedaily.com/releases/2012/11/121118141410.htm A professor has found congresswomen consistently outperform their male counterparts on several measures of job performance.Sun, 18 Nov 2012 14:14:14 ESThttp://www.sciencedaily.com/releases/2012/11/121118141410.htmNew bulimia treatment developedhttp://www.sciencedaily.com/releases/2012/11/121118141408.htm An eating disorders research team has developed a successful bulimia nervosa therapy that can provide patients an alternative for treating this debilitating disorder.Sun, 18 Nov 2012 14:14:14 ESThttp://www.sciencedaily.com/releases/2012/11/121118141408.htmVirtual reality could spot real-world cognitive impairmentshttp://www.sciencedaily.com/releases/2012/11/121118141406.htm A virtual reality test might do a better job than pencil-and-paper tests of predicting whether a cognitive impairment will have real-world consequences. The test uses a computer-game-like virtual world and asks volunteers to navigate their ways through tasks such as delivering packages or running errands around town.Sun, 18 Nov 2012 14:14:14 ESThttp://www.sciencedaily.com/releases/2012/11/121118141406.htm

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